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PRP and Knee Osteoarthritis: Reclaiming Active Lifestyles

For many, knee osteoarthritis (OA) isn't just a medical term; it's an interruption, a pause button on a life that once thrived on movement and activity. Whether you're a 45-year-old executive rushing between meetings, an avid golfer, a marathon enthusiast, or someone who cherishes weekend hikes, when knee pain asserts itself, it disrupts more than just the physical – it touches the core of passions, ambitions, and daily rhythms. Enter the world of Platelet-rich plasma (PRP) therapy: a beacon of hope, using the magic of our body's inherent healing properties to counter the debilitating effects of knee OA.

Unpacking PRP's Magic

PRP therapy falls under the canopy of regenerative medicine. It involves drawing the patient's blood, processing it into platelet rich plasma, and then injecting this concentrated formula into the affected joint. But what makes platelets the heroes of this story? Platelets are naturally equipped with growth factors. Upon release, these proteins hasten tissue repair, dampen inflammation, and likely boost the synthesis of hyaluronic acid, ensuring joints glide smoothly. Several landmark studies published in renowned orthopedic journals spotlight the efficacy of PRP. One notable piece in the Journal of Orthopaedic Research echoes these findings, showing PRP's potential in delaying OA's degenerative progression.

Beyond the Physical Discomfort

Knee OA's challenge goes beyond the mere physical. It's about the adventures left unexplored, the sports matches missed, the dance lessons skipped, and the simple joys of chasing after one's kids or grandkids. The limitations knee OA imposes can touch every sphere of life, from professional commitments to personal aspirations. It can cast a shadow on one's mental well-being, ushering in feelings of desolation and frustration.

PRP: A Step Towards a Brighter Tomorrow While knee osteoarthritis remains a nuanced condition with no one-size-fits-all remedy, PRP emerges as a ray of hope for many. With its minimally invasive nature, it holds the promise of managing, if not reversing, some of OA's debilitating symptoms, paving the way for individuals to reclaim their active lifestyles. In conclusion, PRP therapy is more than just a medical procedure; it's a message of optimism. For those unwilling to let knee pain sideline them, it beckons a chance to rewrite their narrative. However, always consult a trusted medical expert before considering any procedure, weighing the potential benefits against the risks. But, with PRP's potential, it’s undoubtedly a path worth exploring.


  1. Filardo, G., Kon, E., Pereira Ruiz, M. T., Vaccaro, F., Guitaldi, R., Di Martino, A., ... & Marcacci, M. (2012). Platelet-rich plasma intra-articular injections for cartilage degeneration and osteoarthritis: preliminary results. Journal of Orthopaedic Research.

  2. Elik H , Doğu B, Yılmaz F, Begoğlu FA , Kuran B. The Efficiency of Platelet Rich Plasma Treatment in patients with knee osteoarthritis. J Back Musculoskelet Rehabil. 2019 May 10. doi: 10.3233/BMR-181374.

  3. Jiabao Chu, Weifeng Duon. Intra-Articular Injections of Platelet-Rich Plasma Decrease Pain and Improve Functional Outcomes than Sham Saline in Patients with Knee Osteoarthritis 10 Jan 2022 Knee Surgery, Sports Traumatology, Arthroscopy

  4. BRENDAN O'CONNELL.The use of PRP injections in the management of knee osteoarthritis. Cell and Tissue Research (2019)376:143–152

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               Deborah Westergaard, MD

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