How Does PRP Work for Back Pain? A Regenerative Approach That Targets the Root Cause

By Deborah Westergaard, MD

Board-Certified in Pain Medicine and Anesthesiology

Regenexx-Affiliate

Pain Experts Dallas–Plano 

Why So Many Back Pain Treatments Fail—and How PRP Works Differently

Pain Isn’t Just About Discs—It’s About Structure, Stability, and Nerves

If you’ve tried everything—physical therapy, anti-inflammatories, even steroid injections—and you're still in pain, the problem may not be what you think.

Most treatments aim to quiet the symptoms. But PRP (Platelet-Rich Plasma) therapy is different. It helps your body restore structure and repair what’s been damaged, especially in the ligaments, joints, and deep spinal stabilizers.

So—how does PRP work for back pain? Let’s break it down.

How PRP Works for Back Pain: A Guide to Targeted Spine Repair

PRP Supports Healing in Joints, Ligaments, and Stabilizing Muscles

To create PRP, we draw your blood (sometimes a lot, depending on your treatment needs) and process it to isolate the healing-rich platelet layer.

We then use live imaging to inject PRP precisely into the tissues causing pain, including:

• Facet joints

• Sacroiliac joints

• Spinal ligaments

• Multifidus muscle (a critical muscle for spinal support)

These structures are often weakened or inflamed in chronic back pain—but rarely treated directly in traditional care.

PRP stimulates repair, improves blood flow, and strengthens the system that holds your spine together.

Platelet Lysate: How We Treat Nerve Pain Without Surgery

A Regenerative Alternative for Nerve Root and Peripheral Entrapments

If your back pain involves radiating leg pain, numbness, or tingling, there’s a good chance the issue involves nerve inflammation or compression.

This is where platelet lysate plays a key role.

Platelet lysate is made by further processing PRP to release powerful growth factors. It’s used to hydrodissect and decompress nerves without steroids or surgery.

We use platelet lysate for:

• Spinal nerve root pain (like sciatica or foraminal stenosis)

• Carpal tunnel syndrome

• Ulnar nerve entrapments

• Other peripheral nerve conditions

Platelet lysate helps calm inflammation and restore nerve function, often when surgery was considered the only option.

Who Can Benefit from PRP for Back Pain?

Ideal for High-Functioning Individuals Who Want Real Recovery

If you're trying to stay active and productive—but your back pain is interfering with your ability to perform—then regenerative spine care may be your next step.

PRP and platelet lysate are ideal if you:

Want to avoid surgery

Have chronic low back pain or sciatica

Are dealing with SI joint or facet joint pain

Have tried cortisone with limited or temporary results

Want a biologic solution, not just a pain-masking injection

Ready to Restore Your Spine Instead of Just Managing Pain?

PRP and Platelet Lysate Are Available at Pain Experts in Dallas and Plano

Now that you understand how PRP works for back pain, you don’t have to settle for temporary relief or aggressive procedures that destroy tissue.

At Pain Experts, we offer a regenerative approach tailored to your unique spinal anatomy—guided by imaging, backed by research, and delivered with expertise.

Schedule your consultation today. Let’s see if PRP or platelet lysate is the right solution for your back, nerves, or spine—and help you return to your full strength.

Schedule Now

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